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Any questions about
the advanced protection of your furry friends?

This is the place to find the answers

How does VECTRA® 3D kill fleas and ticks on my dog?

VECTRA® 3D protects because of the triple-action formula of Dinotefuran, Pyriproxifen and Permethrin. These ingredients work together to kill fleas and ticks on contact and repel these dangerous parasites.

Once they land on your dog, the parasites come into contact with the treated skin and hairs. The more they move on the dog to find a location to bite, the more they are exposed to the active ingredients of VECTRA® 3D and the sooner they are affected.

In ticks, VECTRA® 3D causes first a “hot foot” reaction. The sensors in the legs of these parasites are very sensitive to permethrin and make the parasite run off the dog (hot foot effect). They are physically compelled to crawl back up the fur, away from the skin, without biting.

In fleas, VECTRA® 3D quickly disrupts the feeding behavior. Within 5 min after infestation and once the product has translocated, feeding is strongly reduced when compared to untreated dogs. Fleas are quickly knocked down and start falling off the animal without possible recovery, thanks to the synergy between dinotefuran and permethrin.

Can VECTRA® 3D be used on pets other than dogs?

No. Do not use VECTRA® 3D on cats, or any other animal.

Do parasites have to bite in order for VECTRA® 3D to work?

No. VECTRA® 3D kills parasites when they come into contact with your pet’s fur.

Is it okay to apply VECTRA® 3D more than once a month?

No, only apply VECTRA® 3D once in a 30-day period. It is not necessary for more frequent applications – VECTRA® 3D provides powerful protection against fleas and ticks for a full month.

Should I remove ticks I see on my dog before applying VECTRA® 3D?

Yes. The sooner ticks are removed from your dog, the better and you prevent the transmission of pathogens to your dogs. Use an appropriate tick removal device. Be sure to remove the entire body of the tick, including mouthparts. Once removed, destroy the tick.

What should I do if my dog exhibits unexpected signs after VECTRA® 3D administration?

Ask your veterinarian for advice.

Does VECTRA® 3D control other parasites besides fleas and ticks?

Yes. VECTRA® 3D is proven to protect your dog for a full month from other major vectors such as mosquitoes, sand flies and biting flies.

What happens to the active ingredients once VECTRA® 3D has been applied?

Following topical application of VECTRA® 3D, the active ingredients move/translocate from the application site to cover the entire body surface within the first few hours and remain for a month.

After topical application of VECTRA® 3D, dinotefuran is partially absorbed through the dog’s skin leading to systemic exposure but this absorption into the body is not relevant for the efficacy.

Pyriproxyfen absorption from VECTRA® 3D through the skin may also occur.

Permethrin from VECTRA® 3D is not absorbed. In the pharmacokinetic study, the plasma levels remained systematically under the limit of quantification.

Is my cat at risk if I use VECTRA® 3D on my dog?

To be at risk, your cat needs to ingest or be in contact with VECTRA® 3D. This can occur if your cat grooms a treated dog and if the application site is not dry yet. To prevent oral exposure of your cat to VECTRA® 3D, we recommend keeping treated dogs away from cats after treatment until the application site is dry. Cats should not be allowed to groom dogs at the application site until the product has dried. Seek veterinary advice immediately if this occurs.

How does VECTRA® 3D control immature stages of fleas?

Immature stages of fleas are hidden in the environment. Inside the house, they are mainly located where the pet sleeps. Flea eggs fall off the animal and develop into larvae. Flea larvae avoid light and live on flea dirt.

They move in random directions but not more than 30-50cm from where the eggs are dropped. Pyriproxyfen, is a highly potent insect growth regulator: it is active at a very low concentration. It disseminates from the treated dog (hairs, skin debris, dust, etc.) and disrupts the development of the immature stages of the fleas. This kills immature fleas, thus preventing emergence of new adults. As demonstrated (Bouhsira et al., 2012), it also sterilizes adult female fleas that are exposed to treated dogs, which prevents egg laying.

Are there possible interactions with other medicinal products?

No, there are no known interactions.

Can I brush my dog after applying VECTRA® 3D?

Yes. VECTRA® 3D remains effective after repeated combing of dogs. However, to reduce your own exposure to the actives, it is recommended not to brush or comb your dog until the application site is dry.

What should I do if my dog licks itself?

Do not worry. VECTRA® 3D has been shown to be safe when ingested at up to 5 times the maximum dose on young dogs. However, to optimize the duration of efficacy of VECTRA® 3D, we recommend you to distract your dog after administration, while VECTRA® 3D dries.

Is it okay for my pet to bathe or swim after applying VECTRA® 3D?

Yes. VECTRA® 3D remains effective in controlling fleas and ticks for a full month if your pet is immersed in water through swimming or bathing. However, for full and sustainable efficacy and for the protection of the environment, it is preferred not to bath or immerse your dog in water until the application site is dry. This may take up to several hours but it is highly variable according to temperature and air exposure. In the studies performed in controlled conditions, the first bathing occurred 48 h after administration and was weekly repeated without reduction in efficacy against fleas or ticks. To protect the environment, we do not recommend that a treated dog enters surface water sources (rivers, streams, sea) for 48 hours after treatment to avoid adverse effects on aquatic organisms.

When is the best time for VECTRA® 3D administration?

We advise that you administer VECTRA® 3D at the end of the day or before taking your dog for a walk.

Once applied, VECTRA® 3D translocates on the dog’s skin and this can lead to unusual sensations for your pet. If your animal is distracted or sleeping while this phenomenon takes place, this will make him more comfortable.

If applied in the evening, the product will have time to dry during the night, thus reducing the possibilities of human exposure.

How quickly does VECTRA® 3D begin to work?

Clinical studies have shown that dogs treated with the active ingredients in VECTRA® 3D, flea feeding is reduced within five minutes and fleas are killed in the first hours – 6 hours for untreated dogs with flea infestations (therapeutic) and 2 hours for dogs that have been treated previously (residual).

VECTRA® 3D is effective against ticks 48 hours after it has been applied.

Onset of activity is also very rapid against flying insects. VECTRA® 3D repels sandflies, mosquitoes and biting flies from 24 h after administration. VECTRA® 3D kills Stomoxys flies within 30 minutes and Aedes mosquitoes within 60 min of exposure to a treated dog.

Does VECTRA® 3D control immature stages of fleas and ticks?

Yes. Immature stages of ticks are more susceptible to active ingredients than adult forms. They are easier to kill.

VECTRA® 3D contains the Insect Growth Regulator pyriproxyfen. It makes VECTRA® 3D truly effective against all immature stages of fleas for 2 months after administration.

What age and body weight does my dog need to be before I can apply VECTRA® 3D?

VECTRA® 3D can be used on puppies as young as 7 weeks of age or > 1.5kg BW.

What are the contraindications of VECTRA® 3D?

VECTRA® 3D is clearly contraindicated for cats. Due to their unique physiology and inability to metabolise permethrin,

VECTRA® 3D must not be used on cats. If applied to a cat, or if ingested by a cat that actively grooms a recently treated dog, VECTRA® 3D may have serious harmful effects. If this occurs, contact your veterinarian immediately.

VECTRA® 3D is also contraindicated in animals with known hypersensitivity to any of the active substances or to any of the excipients.

What if VECTRA® 3D comes into contact with delicate fabrics or materials?

VECTRA® 3D can stain some susceptible fabrics and other materials. We recommend administering VECTRA® 3D outside or in a room away from susceptible surfaces. You should wait until the application site is dry before allowing your dog to come into contact with susceptible materials or surfaces. Make sure that your dog does not shake after administration. If VECTRA® 3D does come into contact with delicate materials then use an absorbent cloth to remove as much of the product as possible before cleaning the surface appropriately.

If a cat is accidentally exposed to VECTRA® 3D, what should I do?

If a cat is accidentally administered VECTRA® 3D, or if it is exposed to VECTRA® 3D from a treated dog the following is recommended:

If administered directly to a cat, bathe the cat with washing up liquid to remove any residual product. Dry the cat well and maintain body temperature. Seek veterinary advice immediately.

If VECTRA® 3D gets in my eyes or on my skin, what should I do?

If in the eyes, hold eye open and rinse slowly and gently with water for 15 to 20 minutes. Remove contact lenses. Contact your doctor for treatment advice.

If swallowed, call a doctor immediately for treatment advice.

If on the skin, take off contaminated clothes. Rinse the skin immediately with plenty of water for 15 to 20 minutes. Call a doctor immediately for treatment advice.

What if VECTRA® Felis gets in contact with fabrics or house material?

VECTRA® Felis can stain some susceptible fabrics and other materials.

This is why you should wait until the application site is dry before allowing your cat to come in contact with your sofa or other susceptible surfaces.

We also recommend administering VECTRA® Felis outside or in a room where susceptible surfaces are not close to your cat.

Make sure that your cat does not shake himself after administration. If contact with material happens, immediately absorb as much as possible of the product with absorbent paper and clean.

If VECTRA® Felis get in my eyes or on my skin, what should I do?

In case of Human exposure to VECTRA® Felis, have the product container or label with you when calling a poison center or doctor or going for treatment.

If in the eyes, hold eye open and rinse slowly and gently with water for 15 to 20 minutes.

Remove contact lenses. Call a poison control center or doctor for treatment advice.

If swallowed, call a poison control center or doctor immediately for treatment advice. Have a person sip a glass of water if able to swallow.

Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything to an unconscious person.

If on the skin, take off contaminated clothes. Rinse the skin immediately with plenty of water for 15 to 20 minutes.

Call a doctor immediately for treatment advice.

What should I do if my cat licks itself?

Do not worry.

VECTRA® Felis has been shown to be safe when ingested at up to 4 times the maximum dose on young cats without adverse effect other than salivation and vomiting.

However, to optimize the duration of efficacy of VECTRA® Felis, we recommend you to distract your cat after administration, while VECTRA® Felis dries.

Why should I worry about immature fleas?

While immature fleas do not feed on the animals, they represent a large proportion of the flea population and will develop into new adults ready to feed on your pet.

Can VECTRA® Felis be used on pets other than cats?

No. Do not use VECTRA® Felis on any other animal.

Can I brush my cat after applying VECTRA® Felis?

Yes. VECTRA® Felis remains effective after repeated combing of cats.

However, to reduce your own exposure to the actives, it is recommended not to brush or comb your cat until the application site is dry.

Is it okay to apply VECTRA® Felis more than once a month?

No, only apply VECTRA® Felis once in a 30-day period.

Unless recommended by your veterinarian, it is not necessary for more frequent applications.

VECTRA® Felis provides powerful protection against fleas for a full month.

Is it okay for my pet to bathe or swim after applying VECTRA® Felis?

This has not been tested. To ensure efficacy and to protect the environment, it is recommended not to bath or immerse your cat in water until the application site is dry.

Do parasites have to bite in order for VECTRA® Felis to work?

No. VECTRA® Felis kills parasites through contact with your pet’s fur. No biting necessary.

Why should I worry about fleas on my cat?

Fleas are small parasites that feed on blood and multiply very quickly. When they bite your cat, they can transmit dangerous diseases to your pet and to your family.

How quickly does VECTRA® Felis begin to work?

Fleas are killed (>95%) within 2 hours

What age does my cat need to be before I can apply VECTRA® Felis?

VECTRA® Felis can be used on kittens as young as 7 weeks of age or at least 0.6kg.

When is the best time for VECTRA® Felis administration?

We advise you to administer VECTRA® Felis at the end of the day.

Are there possible interactions with other medicinal products?

No, there are no known interactions.

What should I do if my cat licks itself?

Do not worry. VECTRA<sup>®</sup> Felis has been shown to be safe when ingested at up to 4 times the maximum dose on young cats without adverse effect other than salivation and vomiting. However, to optimize the duration of efficacy of VECTRA Felis<sup>®</sup>, we recommend you to distract your cat after administration, while VECTRA<sup>®</sup> Felis dries.

How does VECTRA® Felis kill fleas on my cat?

VECTRA® Felis protects because of the double-action formula of dinotefuran and pyriproxifen. These ingredients work together to kill fleas on contact.